Comprehensive transcript-level analysis reveals transcriptional reprogramming during the progression of Alzheimer’s disease

Comprehensive transcript-level analysis reveals transcriptional reprogramming during the progression of Alzheimer’s disease

BackgroundAlzheimer’s disease (AD) is a common neurodegenerative disorder that has a multi-step disease progression. Differences between moderate and advanced stages of AD have not yet been fully characterized.Materials and methodsHerein, we performed a transcript-resolution analysis in 454 AD-relat...

Full description

Bibliographic Details
Main Authors: Hao Wu, Jiao Wang, Xiaoyuan Hu, Cheng Zhuang, Jianxin Zhou, Peiru Wu, Shengli Li, Robert Chunhua Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
transcript expression
alternative splicing
Alzheimer’s disease
isoform switch
RNA binding proteins
asymptomatic AD
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1191680/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2023.1191680/full

Similar Items