Role of indoleamine 2,3-dioxygenase in pathology of the gastrointestinal tract

Indoleamine 2,3-dioxygenase (IDO) has the most important role in modulation of tryptophan-dependent effects in the gastrointestinal tract, including modulation of intestinal immune response. An increased IDO activity maintains immune tolerance and attenuates ongoing inflammation but allows immune es...

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Bibliographic Details
Main Authors: Aleksandar Acovic, Marina Gazdic, Nemanja Jovicic, C. Randall Harrell, Crissy Fellabaum, Nebojsa Arsenijevic, Vladislav Volarevic
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Therapeutic Advances in Gastroenterology
Online Access:https://doi.org/10.1177/1756284818815334