Fasting induces IL-1 resistance and free fatty acid-mediated up-regulation of IL-1R2 and IL-1RA

Fasting induces IL-1 resistance and free fatty acid-mediated up-regulation of IL-1R2 and IL-1RA

Objective: Weight loss is a near societal obsession and many diet programs use significant calorie restriction (CR) including fasting/short term starvation to generate rapid effects. Fasting is also a well-recognized cause of immunosuppression especially within the innate immune system. In this stud...

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Bibliographic Details
Main Authors: jenifer j joesting, morgan l moon, stephan j gainey, brittany l tisza, Neil A Blevins, Gregory G Freund
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Immunology
Subjects:
Starvation
IL-1
free fatty acids
IL1R2
IL-1 receptor type II
IL-1 decoy receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00315/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00315/full

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