Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins

Translation Stress Positively Regulates MscL-Dependent Excretion of Cytoplasmic Proteins

ABSTRACT The apparent mislocalization or excretion of cytoplasmic proteins is a commonly observed phenomenon in both bacteria and eukaryotes. However, reports on the mechanistic basis and the cellular function of this so-called “nonclassical protein secretion” are limited. Here we report that protei...

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Bibliographic Details
Main Authors: Rosa Morra, Francesco Del Carratore, Howbeer Muhamadali, Luminita Gabriela Horga, Samantha Halliwell, Royston Goodacre, Rainer Breitling, Neil Dixon
Format: Article
Language:English
Published: American Society for Microbiology 2018-03-01
Series:mBio
Subjects:
ArfA
MscL
osmotic stress
protein excretion
translation stress
Online Access:https://journals.asm.org/doi/10.1128/mBio.02118-17

Internet

https://journals.asm.org/doi/10.1128/mBio.02118-17

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