A Game of Clones: The Complex Interplay of Aplastic Anaemia, Myelodysplastic Syndrome, and Paroxysmal Nocturnal Haemoglobinuria

A Game of Clones: The Complex Interplay of Aplastic Anaemia, Myelodysplastic Syndrome, and Paroxysmal Nocturnal Haemoglobinuria

Although idiopathic aplastic anaemia (AA), myelodysplastic syndrome (MDS), and paroxysmal nocturnal haemoglobinuria (PNH) are all associated with bone marrow failure, they have traditionally been understood as distinct diseases with sharply contrasting pathophysiologies. These three disorders show c...

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Bibliographic Details
Main Authors: Hayeong Rho, Richard A Wells
Format: Article
Language:English
Published: European Medical Journal 2018-09-01
Series:European Medical Journal
Subjects:
aplastic anaemia (aa)
bone marrow disorder
clonal haematopoeisis
immune escape hypothesis
myelodysplastic syndrome (mds)
paroxysmal nocturnal haemoglobinuria (pnh)
relative growth advantage hypothesis
Online Access:https://www.emjreviews.com/hematology/article/a-game-of-clones-the-complex-interplay-of-aplastic-anaemia-myelodysplastic-syndrome-and-paroxysmal-nocturnal-haemoglobinuria/

Internet

https://www.emjreviews.com/hematology/article/a-game-of-clones-the-complex-interplay-of-aplastic-anaemia-myelodysplastic-syndrome-and-paroxysmal-nocturnal-haemoglobinuria/

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