Double Strand Breaks and Cell-Cycle Arrest Induced by the Cyanobacterial Toxin Cylindrospermopsin in HepG2 Cells

The newly emerging cyanobacterial cytotoxin cylindrospermopsin (CYN) is increasingly found in surface freshwaters, worldwide. It poses a potential threat to humans after chronic exposure as it was shown to be genotoxic in a range of test systems and is potentially carcinogenic. However, the mechanis...

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Bibliographic Details
Main Authors: Bojana Žegura, Matjaž Novak, Metka Filipič, Štraser Alja
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Marine Drugs
Subjects:
Online Access:http://www.mdpi.com/1660-3397/11/8/3077