Detection of CWD prions in urine and saliva of deer by transgenic mouse bioassay.

Chronic wasting disease (CWD) is a prion disease affecting captive and free-ranging cervids (e.g. deer, elk, and moose). The mechanisms of CWD transmission are poorly understood, though bodily fluids are thought to play an important role. Here we report the presence of infectious prions in the urine...

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Bibliographic Details
Main Authors: Nicholas J Haley, Davis M Seelig, Mark D Zabel, Glenn C Telling, Edward A Hoover
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2654070?pdf=render