Advances in omics-based methods to identify novel targets for malaria and other parasitic protozoan infections

Abstract A major advance in antimalarial drug discovery has been the shift towards cell-based phenotypic screening, with notable progress in the screening of compounds against the asexual blood stage, liver stage, and gametocytes. A primary method for drug target deconvolution in Plasmodium falcipar...

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Bibliographic Details
Main Authors: Annie N. Cowell, Elizabeth A. Winzeler
Format: Article
Language:English
Published: BMC 2019-10-01
Series:Genome Medicine
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13073-019-0673-3