mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

mRNA-LNP expressing PfCSP and Pfs25 vaccine candidates targeting infection and transmission of Plasmodium falciparum

Abstract Malaria is a deadly disease responsible for between 550,000 and 627,000 deaths annually. There is a pressing need to develop vaccines focused on malaria elimination. The complex lifecycle of Plasmodium falciparum provides opportunities not only to target the infectious sporozoite stage, int...

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Bibliographic Details
Main Authors: Clifford T. H. Hayashi, Yi Cao, Leor C. Clark, Abhai K. Tripathi, Fidel Zavala, Garima Dwivedi, James Knox, Mohamad-Gabriel Alameh, Paulo J. C. Lin, Ying K. Tam, Drew Weissman, Nirbhay Kumar
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-022-00577-8

Internet

https://doi.org/10.1038/s41541-022-00577-8

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