Experimental Models for Investigating Intra-Stromal Migration of Corneal Keratocytes, Fibroblasts and Myofibroblasts

Experimental Models for Investigating Intra-Stromal Migration of Corneal Keratocytes, Fibroblasts and Myofibroblasts

Following laser vision correction, corneal keratocytes must repopulate areas of cell loss by migrating through the intact corneal stroma, and this can impact corneal shape and transparency. In this study, we evaluate 3D culture models for simulating this process in vitro. Buttons (8 mm diameter) wer...

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Bibliographic Details
Main Authors: Lisha Ma, Walter Matthew Petroll, Neema Lakshman
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Journal of Functional Biomaterials
Subjects:
extracellular matrix
corneal keratocytes
cell mechanics
growth factors
3D culture
Online Access:http://www.mdpi.com/2079-4983/3/1/183/

Internet

http://www.mdpi.com/2079-4983/3/1/183/

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