Generation of an induced pluripotent stem cell line from a Huntington’s disease patient with a long HTT-PolyQ sequence

Generation of an induced pluripotent stem cell line from a Huntington’s disease patient with a long HTT-PolyQ sequence

Huntington’s disease (HD) is an inherited neurodegenerative disorder caused by an abnormal length of CAG repeats in the gene HTT, leading to an elongated poly-glutamine (poly-Q) sequence in huntingtin (HTT). We used non-integrative Sendai virus to reprogram fibroblasts from a patient with juvenile o...

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Bibliographic Details
Main Authors: Duncan C. Miller, Pawel Lisowski, Carolin Genehr, Erich E. Wanker, Josef Priller, Alessandro Prigione, Sebastian Diecke
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506123000429

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http://www.sciencedirect.com/science/article/pii/S1873506123000429

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