All About (NK Cell-Mediated) Death in Two Acts and an Unexpected Encore: Initiation, Execution and Activation of Adaptive Immunity

All About (NK Cell-Mediated) Death in Two Acts and an Unexpected Encore: Initiation, Execution and Activation of Adaptive Immunity

NK cells are key mediators of immune cell-mediated cytotoxicity toward infected and transformed cells, being one of the main executors of cell death in the immune system. NK cells recognize target cells through an array of inhibitory and activating receptors for endogenous or exogenous pathogen-deri...

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Bibliographic Details
Main Authors: Ariel Ramírez-Labrada, Cecilia Pesini, Llipsy Santiago, Sandra Hidalgo, Adanays Calvo-Pérez, Carmen Oñate, Alejandro Andrés-Tovar, Marcela Garzón-Tituaña, Iratxe Uranga-Murillo, Maykel A. Arias, Eva M. Galvez, Julián Pardo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
NK cells
cell death
granzymes
perforin
granule exocytosis
death receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.896228/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.896228/full

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