Anthocyanin-Rich Grape Pomace Extract (Vitis vinifera L.) from Wine Industry Affects Mitochondrial Bioenergetics and Glucose Metabolism in Human Hepatocarcinoma HepG2 Cells

Anthocyanin-Rich Grape Pomace Extract (Vitis vinifera L.) from Wine Industry Affects Mitochondrial Bioenergetics and Glucose Metabolism in Human Hepatocarcinoma HepG2 Cells

Cancer cells demand high ATP provisions to support proliferation, and targeting of energy metabolism is a good strategy to increase their sensitivity to treatments. In Brazil, wine manufacture is expanding, increasing the amount of pomace that is produced. We determined the phenolic composition and...

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Bibliographic Details
Main Authors: Nathalia F. F. de Sales, Leandro Silva da Costa, Talita I. A. Carneiro, Daniela A. Minuzzo, Felipe L. Oliveira, Lourdes M. C. Cabral, Alexandre G. Torres, Tatiana El-Bacha
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Molecules
Subjects:
grape pomace
anthocyanins
polyphenols
bioactivity
cancer
mitochondrial bioenergetics
glucose metabolism
in vitro
HepG2 cells
Online Access:http://www.mdpi.com/1420-3049/23/3/611

Internet

http://www.mdpi.com/1420-3049/23/3/611

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