Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice

Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice

Proprotein convertases (PCSKs) process matrix metalloproteases and cytokines, but their function in the vasculature is largely unknown. Previously, we demonstrated upregulation of PCSK6 in atherosclerotic plaques from symptomatic patients, localization to smooth muscle cells (SMCs) in the fibrous ca...

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Bibliographic Details
Main Authors: Samuel Röhl, Bianca E. Suur, Mariette Lengquist, Till Seime, Kenneth Caidahl, Ulf Hedin, Anders Arner, Ljubica Matic, Anton Razuvaev
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
vessel wall remodeling
pro-protein convertase subtilisin/kexin 6
smooth muscle cells
Online Access:https://www.mdpi.com/2073-4409/9/4/1009

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https://www.mdpi.com/2073-4409/9/4/1009

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