Oseltamivir is adequately absorbed following nasogastric administration to adult patients with severe H5N1 influenza.

Oseltamivir is adequately absorbed following nasogastric administration to adult patients with severe H5N1 influenza.

In the absence of a parenteral drug, oral oseltamivir is currently recommended by the WHO for treating H5N1 influenza. Whether oseltamivir absorption is adequate in severe influenza is unknown. We measured the steady state, plasma concentrations of nasogastrically administered oseltamivir 150 mg bid...

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Bibliographic Details
Main Authors: Walter R J Taylor, Bui Nghia Thinh, Giang Thuc Anh, Peter Horby, Heiman Wertheim, Niklas Lindegardh, Menno D de Jong, Kasia Stepniewska, Tran Thuy Hanh, Nguyen Duc Hien, Ngo Minh Bien, Ngo Quy Chau, Annette Fox, Nghiem My Ngoc, Martin Crusat, Jeremy J Farrar, Nicholas J White, Nguyen Hong Ha, Trinh Thi Lien, Nguyen Vu Trung, Nicholas Day, Nguyen Gia Binh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2565445?pdf=render

Internet

http://europepmc.org/articles/PMC2565445?pdf=render

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