The p16 Antagonist Gankyrin Is Overexpressed in Melanocytic Neoplasms
Gankyrin has a household function in essentially all cells by acting as a chaperone in the assembly of the 26S proteasome, but also functions as a tumor-promoting protein by antagonizing the tumor suppressors retinoblastoma protein, p16, and p53. While gankyrin is overexpressed in many neoplasms out...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-11-01
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Series: | Journal of Molecular Pathology |
Subjects: | |
Online Access: | https://www.mdpi.com/2673-5261/3/4/27 |