The p16 Antagonist Gankyrin Is Overexpressed in Melanocytic Neoplasms

Gankyrin has a household function in essentially all cells by acting as a chaperone in the assembly of the 26S proteasome, but also functions as a tumor-promoting protein by antagonizing the tumor suppressors retinoblastoma protein, p16, and p53. While gankyrin is overexpressed in many neoplasms out...

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Bibliographic Details
Main Authors: Sara Moradi, Torsten Ehrig
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Journal of Molecular Pathology
Subjects:
Online Access:https://www.mdpi.com/2673-5261/3/4/27