Evaluation of the Potential Impact of Ebola Virus Genomic Drift on the Efficacy of Sequence-Based Candidate Therapeutics

ABSTRACT  Until recently, Ebola virus (EBOV) was a rarely encountered human pathogen that caused disease among small populations with extraordinarily high lethality. At the end of 2013, EBOV initiated an unprecedented disease outbreak in West Africa that is still ongoing and has already caused thous...

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Bibliographic Details
Main Authors: Jeffrey R. Kugelman, Mariano Sanchez-Lockhart, Kristian G. Andersen, Stephen Gire, Daniel J. Park, Rachel Sealfon, Aaron E. Lin, Shirlee Wohl, Pardis C. Sabeti, Jens H. Kuhn, Gustavo F. Palacios
Format: Article
Language:English
Published: American Society for Microbiology 2015-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.02227-14