Circulating tumor cells from melanoma patients show phenotypic plasticity and metastatic potential in xenograft NOD.CB17 mice

Circulating tumor cells from melanoma patients show phenotypic plasticity and metastatic potential in xenograft NOD.CB17 mice

Abstract Background Innovative therapies have improved the overall survival in melanoma, although a high number of patients still experience disease progression or recurrence. Ex-vivo culture of circulating tumour cells (CTCs) represents a valuable laboratory resource for in-depth characterization o...

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Bibliographic Details
Main Authors: Claudia Felici, Francesco Mannavola, Luigia Stefania Stucci, Loren Duda, Paola Cafforio, Camillo Porta, Marco Tucci
Format: Article
Language:English
Published: BMC 2022-07-01
Series:BMC Cancer
Subjects:
Melanoma
Circulating tumor cells
Phenotypic plasticity
Stemness
Metastases; NOD.CB17 mice
Online Access:https://doi.org/10.1186/s12885-022-09829-1

Internet

https://doi.org/10.1186/s12885-022-09829-1

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