Na+/Ca2+ Exchanger Inhibitors Inhibit Neurite Outgrowth in PC12 Cells

Abstract.: To elucidate the role of Na+/Ca2+ exchanger (NCX) in neurite outgrowth, we investigated the effects of NCX inhibitors on neurite outgrowth in PC12 cells. KB-R7943 and 3′,4′dichlorobenzamil, NCX inhibitors, inhibited the neurite outgrowth caused by nerve growth factor (NGF). NCX inhibitors...

Full description

Bibliographic Details
Main Authors: Toru Oda, Toshiaki Kume, Yasuhiko Izumi, Kumatoshi Ishihara, Hachiro Sugmimoto, Akinori Akaike
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319307297