Polyphenol Metabolite Pyrogallol-<i>O</i>-Sulfate Decreases Microglial Activation and VEGF in Retinal Pigment Epithelium Cells and Diabetic Mouse Retina

Polyphenol Metabolite Pyrogallol-<i>O</i>-Sulfate Decreases Microglial Activation and VEGF in Retinal Pigment Epithelium Cells and Diabetic Mouse Retina

(Poly)phenol-derived metabolites are small molecules resulting from (poly)phenol metabolization after ingestion that can be found in circulation. In the last decade, studies on the impact of (poly)phenol properties in health and cellular metabolism accumulated evidence that (poly)phenols are benefic...

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Bibliographic Details
Main Authors: Daniela F. Santos, Mariana Pais, Cláudia N. Santos, Gabriela A. Silva
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
diabetic retinopathy
inflammation
neovascularization
retinal pigment epithelium
hyperglycemia
Online Access:https://www.mdpi.com/1422-0067/22/21/11402

Internet

https://www.mdpi.com/1422-0067/22/21/11402

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