BET in hematologic tumors: Immunity, pathogenesis, clinical trials and drug combinations

The bromodomain and extra-terminal (BET) proteins act as “readers” for lysine acetylation and facilitate the recruitment of transcriptional elongation complexes. BET protein is associated with transcriptional elongation of genes such as c-MYC and BCL-2, and is involved in the regulation of cell cycl...

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Bibliographic Details
Main Authors: Tao Ma, Yan Chen, Zhi-Gang Yi, Yan-Hong Li, Jun Bai, Li-Juan Li, Lian-Sheng Zhang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-11-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222000733