Expression of Tgfβ1 and inflammatory markers in the 6-hydroxydopamine mouse model of Parkinson´s disease

Expression of Tgfβ1 and inflammatory markers in the 6-hydroxydopamine mouse model of Parkinson´s disease

Parkinson´s disease (PD) is a neurodegenerative disorder that is characterised by loss of midbrain dopaminergic (mDA) neurons in the substantia nigra (SN). Microglia-mediated neuroinflammation has been described as a common hallmark of PD and is believed to further trigger the progression of neurode...

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Bibliographic Details
Main Authors: Stefan Jean-Pierre Haas, Xiaolai eZhou, Venissa eMachado, Andreas eWree, Kerstin eKrieglstein, Björn eSpittau
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-02-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Astrocytes
Microglia
TNFα
6-OHDA
TGFβ1
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00007/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnmol.2016.00007/full

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