Identification and characterization of shark VNARs targeting the Helicobacter pylori adhesin HpaA

Identification and characterization of shark VNARs targeting the Helicobacter pylori adhesin HpaA

AbstractHelicobacter pylori (H. pylori) is recognized as a pathogen associated with several gastrointestinal diseases. The current treatments exhibit numerous drawbacks, including antibiotic resistance. H. pylori can adhere to and colonize the gastric mucosa through H. pylori adhesin A (HpaA), and a...

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Bibliographic Details
Main Authors: Yanchun Gao, Ruihong Wang, Lin Liu, Shitao Feng, Xiaozhi Xi, Wengong Yu, Yuchao Gu, Ye Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Artificial Cells, Nanomedicine, and Biotechnology
Subjects:
Helicobacter pylori
HpaA
phage display
shark VNAR
single-domain antibody
nanobody
Online Access:https://www.tandfonline.com/doi/10.1080/21691401.2023.2255635

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https://www.tandfonline.com/doi/10.1080/21691401.2023.2255635

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