CAR T Cell Therapy in Glioblastoma: Overcoming Challenges Related to Antigen Expression

Glioblastoma (GBM) is the most common primary brain tumor, yet prognosis remains dismal with current treatment. Immunotherapeutic strategies have had limited effectiveness to date in GBM, but recent advances hold promise. One such immunotherapeutic advance is chimeric antigen receptor (CAR) T cell t...

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Bibliographic Details
Main Authors: Andrew S. Luksik, Eli Yazigi, Pavan Shah, Christopher M. Jackson
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/15/5/1414