Mass Cytometry and Single-Cell Transcriptome Analyses Reveal the Immune Cell Characteristics of Ulcerative Colitis

Background: The pathogenesis of ulcerative colitis (UC) is closely related to immunity. The immune characteristic differences between active UC (UCa) and inactive UC (UCin) have not been completely explained. Mass cytometry (CyTOF) and single-cell RNA sequencing (scRNA-seq) were used to analyze the...

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Bibliographic Details
Main Authors: Yongxin Luo, Shiying Liu, Huibiao Li, Jiangtao Hou, Wenjia Lin, Zewen Xu, Tianyu Lu, Yanwu Li, Bin Peng, Shijing Zhang, Xue Han, Zuoliang Kuang, Yi Wen, Jiazhong Cai, Fengbin Liu, Xin-Lin Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.859645/full