NF-κB is activated in CD4+ iNKT cells by sickle cell disease and mediates rapid induction of adenosine A2A receptors.
Reperfusion injury following tissue ischemia occurs as a consequence of vaso-occlusion that is initiated by activation of invariant natural killer T (iNKT) cells. Sickle cell disease (SDC) results in widely disseminated microvascular ischemia and reperfusion injury as a result of vaso-occlusion by r...
| Auteurs principaux: | , , , , , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Public Library of Science (PLoS)
2013-01-01
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| Collection: | PLoS ONE |
| Accès en ligne: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24124453/?tool=EBI |