Durability and cross-reactivity of immune responses induced by a plant-based virus-like particle vaccine for COVID-19

Here, the authors report results from a Phase 1 trial with an AS03-adjuvanted, plant-based virus-like particle displaying the spike protein of the ancestral SARS-CoV-2. Six months post-second dose, they observe good neutralizing antibody titers and T cell responses to ancestral virus and variants of...

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Bibliographic Details
Main Authors: Philipe Gobeil, Stéphane Pillet, Iohann Boulay, Nathalie Charland, Aurélien Lorin, Matthew P. Cheng, Donald C. Vinh, Philippe Boutet, Robbert Van Der Most, François Roman, Maria Angeles Ceregido, Nathalie Landry, Marc-André D’Aoust, Brian J. Ward
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34728-1