Kinetically-defined component actions in gene repression.

Gene repression by transcription factors, and glucocorticoid receptors (GR) in particular, is a critical, but poorly understood, physiological response. Among the many unresolved questions is the difference between GR regulated induction and repression, and whether transcription cofactor action is t...

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Bibliographic Details
Main Authors: Carson C Chow, Kelsey K Finn, Geoffery B Storchan, Xinping Lu, Xiaoyan Sheng, S Stoney Simons
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4376387?pdf=render