The crosstalk between glomerular endothelial cells and podocytes controls their responses to metabolic stimuli in diabetic nephropathy

The crosstalk between glomerular endothelial cells and podocytes controls their responses to metabolic stimuli in diabetic nephropathy

Abstract In diabetic nephropathy (DN), glomerular endothelial cells (GECs) and podocytes undergo pathological alterations, which are influenced by metabolic changes characteristic of diabetes, including hyperglycaemia (HG) and elevated methylglyoxal (MGO) levels. However, it remains insufficiently u...

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Bibliographic Details
Main Authors: Michael Albrecht, Carsten Sticht, Tabea Wagner, Steffen A. Hettler, Carolina De La Torre, Jiedong Qiu, Norbert Gretz, Thomas Albrecht, Benito Yard, Jonathan P. Sleeman, Boyan K. Garvalov
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-45139-7

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https://doi.org/10.1038/s41598-023-45139-7

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