Endotoxin Modulates the Expression of Renal Drug Transporters in HIV-1 Transgenic Rats

PURPUSE: Bacterial co-infections and low grade endotoxemia are common in HIV patients. Inflammation due to endotoxin or HIV may influence the expression and activity of transporters. Kidney transporters influence renal drug clearances including many antiretroviral agents. Our objective was to study...

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Bibliographic Details
Main Authors: Navaz Karimian Pour, Micheline Piquette-Miller
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Journal of Pharmacy & Pharmaceutical Sciences
Online Access:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/30017