Overexpression of POLA2 in hepatocellular carcinoma is involved in immune infiltration and predicts a poor prognosis

Overexpression of POLA2 in hepatocellular carcinoma is involved in immune infiltration and predicts a poor prognosis

Abstract Background Hepatocellular carcinoma (HCC) is the second malignancy worldwide. POLA2 initiates DNA replication, regulates cell cycle and gene repair that promote tumorigenesis and disease progression. However, the prognostic and biological function roles of POLA2 in HCC had not been conclusi...

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Bibliographic Details
Main Authors: Long Liu, Qi Wang, Linjun Wu, Lele Zhang, Yuxi Huang, Haihua Yang, Le guo, Zheping Fang, Xuequan Wang
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Cancer Cell International
Subjects:
POLA2
Hepatocellular carcinoma
Prognostic
Immune infiltration
DNA polymerase α
Online Access:https://doi.org/10.1186/s12935-023-02949-z

Internet

https://doi.org/10.1186/s12935-023-02949-z

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