Massive A-to-I RNA editing is common across the Metazoa and correlates with dsRNA abundance

Abstract Background Adenosine to inosine (A-to-I) RNA editing is a post-transcriptional modification catalyzed by the ADAR (adenosine deaminase that acts on RNA) enzymes, which are ubiquitously expressed among metazoans. Technical requirements have limited systematic mapping of editing sites to a sm...

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Bibliographic Details
Main Authors: Hagit T. Porath, Binyamin A. Knisbacher, Eli Eisenberg, Erez Y. Levanon
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-017-1315-y