Multimodal analysis of the differential effects of cyclic strain on collagen isoform composition, fibril architecture and biomechanics of tissue engineered tendon

Tendon is predominantly composed of aligned type I collagen, but additional isoforms are known to influence fibril architecture and maturation, which contribute to the tendon’s overall biomechanical performance. The role of the less well-studied collagen isoforms on fibrillogenesis in tissue enginee...

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Bibliographic Details
Main Authors: Adam J Janvier, Emily G Pendleton, Luke J Mortensen, Daniel C Green, James R Henstock, Elizabeth G Canty-Laird
Format: Article
Language:English
Published: SAGE Publishing 2022-10-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314221130486