Assessment of 9-OH- and 7,8-diol-benzo[a]pyrene in Blood as Potent Markers of Cognitive Impairment Related to benzo[a]pyrene Exposure: An Animal Model Study

Assessment of 9-OH- and 7,8-diol-benzo[a]pyrene in Blood as Potent Markers of Cognitive Impairment Related to benzo[a]pyrene Exposure: An Animal Model Study

The potent neurotoxicity of benzo[a]pyrene (B[a]P) has been suggested to be a susceptibility factor accelerating the onset of brain tumours and the emergence of neurobehavioural disturbances. B[a]P has been shown to be neurotoxic, acting directly on both the central and peripheral nervous systems, a...

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Bibliographic Details
Main Authors: Lynda Saber Cherif, Lei Cao-Lei, Sophie Farinelle, Claude P. Muller, Jonathan D. Turner, Henri Schroeder, Nathalie Grova
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Toxics
Subjects:
benzo[a]pyrene
oral exposure
9-OHbenzo[a]pyrene 7,8-diol-benzo[a]pyrene
biomarker of neurotoxicity
cognitive impairments
NMDA receptor
Online Access:https://www.mdpi.com/2305-6304/9/3/50

Internet

https://www.mdpi.com/2305-6304/9/3/50

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