Comprehensive analysis of alternative polyadenylation regulators concerning CD276 and immune infiltration in bladder cancer

Comprehensive analysis of alternative polyadenylation regulators concerning CD276 and immune infiltration in bladder cancer

Abstract Alternative polyadenylation (APA) is emerging as a crucial regulatory mechanism in bladder cancer (BC), while it remains elusive whether APA influences the tumor immune microenvironment (TIME) in BC. We identified two distinct subtypes of BC by APA-related regulatory genes expression profil...

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Bibliographic Details
Main Authors: Ming Xiong, Wencheng Li, Longwang Wang, Liang Chen, Zhaohui Chen, Chengcheng Wei, Futian Zhang, Jiawei Chen, Gallina Kazobinka, Jun Zhao, Teng Hou
Format: Article
Language:English
Published: BMC 2022-09-01
Series:BMC Cancer
Subjects:
Alternative polyadenylation
Bladder cancer
Immune infiltration
Immunotherapy target
CPSF3
CD276
Online Access:https://doi.org/10.1186/s12885-022-10103-7

Internet

https://doi.org/10.1186/s12885-022-10103-7

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