Loss of mfsd8 alters the secretome during Dictyostelium aggregation
Major facilitator superfamily domain-containing protein 8 (MFSD8) is a transmembrane protein that has been reported to function as a lysosomal chloride channel. In humans, homozygous mutations in MFSD8 cause a late-infantile form of neuronal ceroid lipofuscinosis (NCL) called CLN7 disease. In the so...
Main Authors: | Robert J. Huber, Joshua Gray, William D. Kim |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-12-01
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Series: | European Journal of Cell Biology |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0171933523000766 |
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