Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X

Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X

Dynamic Ca2+ signals reflect acute changes in membrane excitability, and also mediate signaling cascades in chronic processes. In both cases, chronic Ca2+ imaging is often desired, but challenged by the cytotoxicity intrinsic to calmodulin (CaM)-based GCaMP, a series of genetically-encoded Ca2+ indi...

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Bibliographic Details
Main Authors: Jinli Geng, Yingjun Tang, Zhen Yu, Yunming Gao, Wenxiang Li, Yitong Lu, Bo Wang, Huiming Zhou, Ping Li, Nan Liu, Ping Wang, Yubo Fan, Yaxiong Yang, Zengcai V Guo, Xiaodong Liu
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-10-01
Series:eLife
Subjects:
genetically encoded calcium indicators
cortical neurons
calmodulin
calcium oscillations
in vivo calcium imaging
neurite outgrowth
Online Access:https://elifesciences.org/articles/76691

Internet

https://elifesciences.org/articles/76691

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