Epithelial-Mesenchymal Transition Is a Critical Step in Tumorgenesis of Pancreatic Neuroendocrine Tumors

Epithelial-Mesenchymal Transition Is a Critical Step in Tumorgenesis of Pancreatic Neuroendocrine Tumors

The transcription factors Snail, Slug and Twist repress E-cadherin and induce epithelial-mesenchymal transition (EMT), a process exploited by invasive cancer cells. In this study, we evaluated the role of EMT in the tumorgenesis of neuroendocrine tumors of the pancreas (PNETs) in vitro, in vivo and...

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Bibliographic Details
Main Authors: Alexander König, Detlef K. Bartsch, Johannes Rehm, Thomas M. Gress, Malte Buchholz, Jens Waldmann, Katja Maschuw, Volker Fendrich
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Cancers
Subjects:
EMT
E-cadherin
snail
slug
twist
Rip1Tag2
PEG
Online Access:http://www.mdpi.com/2072-6694/4/1/281/

Internet

http://www.mdpi.com/2072-6694/4/1/281/

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