MicroRNA-217 attenuates intima–media complex thickness of ascending aorta measured by ultrasound bio-microscopy and inhibits inflammation and lipid metabolism in atherosclerotic models of ApoE−/− mice

MicroRNA-217 attenuates intima–media complex thickness of ascending aorta measured by ultrasound bio-microscopy and inhibits inflammation and lipid metabolism in atherosclerotic models of ApoE−/− mice

Abstract Background Little investigation was done to test the efficiency of microRNA-217 (miR-217) on atherosclerosis in vivo. Methods ApoE−/− mice were used to construct atherosclerotic models and ultrasound bio-microscopy (UBM) was applied to detect the intima–media thickness (IMT) of the ascendin...

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Bibliographic Details
Main Authors: Haina Liu, Xia Li, Yanpeng Song, Zhibin Wang
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Lipids in Health and Disease
Subjects:
MicroRNA-217
Atherosclerosis
Ultrasound bio-microscopy
Inflammation
Lipid
Online Access:http://link.springer.com/article/10.1186/s12944-018-0825-2

Internet

http://link.springer.com/article/10.1186/s12944-018-0825-2

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