In Silico Investigation of AKT2 Gene and Protein Abnormalities Reveals Potential Association with Insulin Resistance and Type 2 Diabetes

In Silico Investigation of AKT2 Gene and Protein Abnormalities Reveals Potential Association with Insulin Resistance and Type 2 Diabetes

Type 2 diabetes (T2D) develops from insulin resistance (IR) and the dysfunction of pancreatic beta cells. The AKT2 protein is very important for the protein signaling pathway, and the non-synonymous SNP (nsSNPs) in AKT2 gene may be associated with T2D. nsSNPs can result in alterations in protein sta...

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Bibliographic Details
Main Authors: M. E. Elangeeb, Imadeldin Elfaki, M. A. Elkhalifa, Khalid M. Adam, A. O. Alameen, Ahmed Kamaleldin Elfadl, Ibrahim Altedlawi Albalawi, Kholoud S. Almasoudi, Reema Almotairi, Basim S. O. Alsaedi, Marwan H. Alhelali, Mohammad Muzaffar Mir, Dnyanesh Amle, Rashid Mir
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Current Issues in Molecular Biology
Subjects:
bioinformatics
nsSNP
protein
AKT2
type 2 diabetes
insulin resistance
Online Access:https://www.mdpi.com/1467-3045/45/9/471

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https://www.mdpi.com/1467-3045/45/9/471

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