Exploring biomarkers of premature ovarian insufficiency based on oxford nanopore transcriptional profile and machine learning

Abstract Premature ovarian insufficiency (POI) is a reproductive endocrine disorder characterized by infertility and perimenopausal syndrome, with a highly heterogeneous genetic etiology and its mechanism is not fully understood. Therefore, we utilized Oxford Nanopore Technology (ONT) for the first...

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Bibliographic Details
Main Authors: Zhaoyang Yu, Mujun Li, Weilong Peng
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-38754-x