Skin microbiota signature distinguishes IBD patients and reflects skin adverse events during anti-TNF therapy

Skin microbiota signature distinguishes IBD patients and reflects skin adverse events during anti-TNF therapy

Crohn’s disease (CD) and ulcerative colitis (UC) are two forms of inflammatory bowel disease (IBD), where the role of gut but not skin dysbiosis is well recognized. Inhibitors of TNF have been successful in IBD treatment, but up to a quarter of patients suffer from unpredictable skin adverse events...

Full description

Bibliographic Details
Main Authors: Zuzana Reiss, Filip Rob, Martin Kolar, Dagmar Schierova, Jakub Kreisinger, Zuzana Jackova, Radka Roubalova, Stepan Coufal, Martin Mihula, Tomas Thon, Lukas Bajer, Michaela Novakova, Martin Vasatko, Klara Kostovcikova, Natalie Galanova, Milan Lukas, Miloslav Kverka, Jana Tresnak Hercogova, Helena Tlaskalova-Hogenova, Zuzana Jiraskova Zakostelska
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
skin microbiota
IBD
16S RNA sequencing
serum biomarker
TNF-alpha antagonist
skin adverse events
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1064537/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1064537/full

Similar Items