Interferon-γ induces immunosuppression in salivary adenoid cystic carcinoma by regulating programmed death ligand 1 secretion

Abstract Interferon-γ (IFN-γ), a key effector molecule in anti-tumor immune response, has been well documented to correlate with the intratumoral infiltration of immune cells. Of interest, however, a high level of IFN-γ has been reported in salivary adenoid cystic carcinoma (SACC), which is actually...

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Bibliographic Details
Main Authors: Qiuyun Fu, Xingchi Liu, Houfu Xia, Yicun Li, Zili Yu, Bing Liu, Xuepeng Xiong, Gang Chen
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:International Journal of Oral Science
Online Access:https://doi.org/10.1038/s41368-022-00197-x