Potential of Vitamin B6 Dioxime Analogues to Act as Cholinesterase Ligands

Potential of Vitamin B6 Dioxime Analogues to Act as Cholinesterase Ligands

Seven pyridoxal dioxime quaternary salts (<b>1</b>–<b>7</b>) were synthesized with the aim of studying their interactions with human acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The synthesis was achieved by the quaternization of pyridoxal monooxime with subs...

Full description

Bibliographic Details
Main Authors: Dajana Gašo Sokač, Antonio Zandona, Sunčica Roca, Dražen Vikić-Topić, Gabriela Lihtar, Nikola Maraković, Valentina Bušić, Zrinka Kovarik, Maja Katalinić
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
pyridoxal oxime
dioxime
AChE
BChE
reversible inhibition
reactivation
Online Access:https://www.mdpi.com/1422-0067/23/21/13388

Internet

https://www.mdpi.com/1422-0067/23/21/13388

Similar Items