Risk-Assessment Implications of Mechanistic Model's Prediction of Low-Dose Nonlinearity of Liver Tumor Risk for Mice FED Fumonisin B
A two-stage, clonal-expansion model of liver tumor risk in mice was developed by Kodell et al. (Food Addit Contam 18:237–253, 2001) based on the hypothesis that fumonisin B 1 , a naturally occurring mycotoxin in corn, is not genotoxic, but rather causes cancer through the disruption of sphingolipid...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2004-01-01
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| Series: | Dose-Response |
| Online Access: | https://doi.org/10.1080/15401420490426981 |