Peptide-Based Physical Gels Endowed with Thixotropic Behaviour
Thixotropy is one of the oldest documented rheological phenomenon in colloid science and may be defined as an increase of viscosity in a state of rest and a decrease of viscosity when submitted to a constant shearing stress. This behavior has been exploited in recent years to prepare injectable hydr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-10-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/3/4/39 |
| _version_ | 1831737430649077760 |
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| author | Nicola Zanna Claudia Tomasini |
| author_facet | Nicola Zanna Claudia Tomasini |
| author_sort | Nicola Zanna |
| collection | DOAJ |
| description | Thixotropy is one of the oldest documented rheological phenomenon in colloid science and may be defined as an increase of viscosity in a state of rest and a decrease of viscosity when submitted to a constant shearing stress. This behavior has been exploited in recent years to prepare injectable hydrogels for application in drug delivery systems. Thixotropic hydrogels may be profitably used in the field of regenerative medicine, which promotes tissue healing after injuries and diseases, as the molten hydrogel may be injected by syringe and then self-adapts in the space inside the injection site and recovers the solid form. We will focus our attention on the preparation, properties, and some applications of biocompatible thixotropic hydrogels. |
| first_indexed | 2024-12-21T13:03:44Z |
| format | Article |
| id | doaj.art-5f3935d5a65241508f136ded726a0c31 |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-12-21T13:03:44Z |
| publishDate | 2017-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-5f3935d5a65241508f136ded726a0c312022-12-21T19:03:06ZengMDPI AGGels2310-28612017-10-01343910.3390/gels3040039gels3040039Peptide-Based Physical Gels Endowed with Thixotropic BehaviourNicola Zanna0Claudia Tomasini1Dipartimento di Chimica “Giacomo Ciamician”—Alma Mater Studiorum Università di Bologna—Via Selmi, 2-40126 Bologna, ItalyDipartimento di Chimica “Giacomo Ciamician”—Alma Mater Studiorum Università di Bologna—Via Selmi, 2-40126 Bologna, ItalyThixotropy is one of the oldest documented rheological phenomenon in colloid science and may be defined as an increase of viscosity in a state of rest and a decrease of viscosity when submitted to a constant shearing stress. This behavior has been exploited in recent years to prepare injectable hydrogels for application in drug delivery systems. Thixotropic hydrogels may be profitably used in the field of regenerative medicine, which promotes tissue healing after injuries and diseases, as the molten hydrogel may be injected by syringe and then self-adapts in the space inside the injection site and recovers the solid form. We will focus our attention on the preparation, properties, and some applications of biocompatible thixotropic hydrogels.https://www.mdpi.com/2310-2861/3/4/39drug deliveryinjectable hydrogelspeptidespeptidomimeticsregenerative medicinerheology |
| spellingShingle | Nicola Zanna Claudia Tomasini Peptide-Based Physical Gels Endowed with Thixotropic Behaviour Gels drug delivery injectable hydrogels peptides peptidomimetics regenerative medicine rheology |
| title | Peptide-Based Physical Gels Endowed with Thixotropic Behaviour |
| title_full | Peptide-Based Physical Gels Endowed with Thixotropic Behaviour |
| title_fullStr | Peptide-Based Physical Gels Endowed with Thixotropic Behaviour |
| title_full_unstemmed | Peptide-Based Physical Gels Endowed with Thixotropic Behaviour |
| title_short | Peptide-Based Physical Gels Endowed with Thixotropic Behaviour |
| title_sort | peptide based physical gels endowed with thixotropic behaviour |
| topic | drug delivery injectable hydrogels peptides peptidomimetics regenerative medicine rheology |
| url | https://www.mdpi.com/2310-2861/3/4/39 |
| work_keys_str_mv | AT nicolazanna peptidebasedphysicalgelsendowedwiththixotropicbehaviour AT claudiatomasini peptidebasedphysicalgelsendowedwiththixotropicbehaviour |