The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β‐catenin signaling in lung cancer

The oncogenic role of LGR6 overexpression induced by aberrant Wnt/β‐catenin signaling in lung cancer

Abstract Background Molecular abnormalities in the Wnt/β‐catenin pathway confer malignant phenotypes in lung cancer. Previously, we identified the association of leucine‐rich repeat‐containing G protein‐coupled receptor 6 (LGR6) with oncogenic Wnt signaling, and its downregulation upon β‐catenin kno...

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Bibliographic Details
Main Authors: Noriaki Sunaga, Kyoichi Kaira, Kimihiro Shimizu, Ichidai Tanaka, Yosuke Miura, Seshiru Nakazawa, Yoichi Ohtaki, Reika Kawabata‐Iwakawa, Mitsuo Sato, Luc Girard, John D. Minna, Takeshi Hisada
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Thoracic Cancer
Subjects:
non‐small cell lung cancer
oncogene
small cell lung cancer
Wnt pathway
β‐catenin
Online Access:https://doi.org/10.1111/1759-7714.15169

Internet

https://doi.org/10.1111/1759-7714.15169

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