Restricting genomic actions of innate immune mediators on fetal hematopoietic progenitor cells

Restricting genomic actions of innate immune mediators on fetal hematopoietic progenitor cells

Summary: Innate immune signaling protects against pathogens, controls hematopoietic development, and functions in oncogenesis, yet the relationship between these mechanisms is undefined. Downregulating the GATA2 transcription factor in fetal hematopoietic progenitor cells upregulates genes encoding...

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Bibliographic Details
Main Authors: Vu L. Tran, Peng Liu, Koichi R. Katsumura, Erin Kim, Bjorn M. Schoff, Kirby D. Johnson, Emery H. Bresnick
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Molecular mechanism of gene regulation
Immunology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223003747

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http://www.sciencedirect.com/science/article/pii/S2589004223003747

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