Original encounter with antigen determines antigen-presenting cell imprinting of the quality of the immune response in mice.

BACKGROUND:Obtaining a certain multi-functionality of cellular immunity for the control of infectious diseases is a burning question in immunology and in vaccine design. Early events, including antigen shuttling to secondary lymphoid organs and recruitment of innate immune cells for adaptive immune...

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Bibliographic Details
Main Authors: Valérie Abadie, Olivia Bonduelle, Darragh Duffy, Christophe Parizot, Bernard Verrier, Béhazine Combadière
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2785484?pdf=render