17beta-estradiol and testosterone influence the mRNA expression and the time course of inflammatory cytokines in activated human monocytic cell line (THP-1)
Objective: The aim of this study was to evaluate the effects of 17b-estradiol (E2) and testosterone (T) on the mRNA expression of IL-1b, IL-6, TNF-a and TGF-b in cultured human monocytic cells (THP-1) after INF-g activation. Methods: THP-1 were cultured with E2 and T (10 nM) for 24 hs and then activ...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
PAGEPress Publications
2011-09-01
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Series: | Reumatismo |
Online Access: | http://www.reumatismo.org/index.php/reuma/article/view/218 |